TP63 (Human) Recombinant Protein (Q01)
产品名称： TP63 (Human) Recombinant Protein (Q01)
英文名称： TP63 (Human) Recombinant Protein (Q01)
产品编号： H00008626-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human TP63 partial ORF ( AAH39815, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MNFETSRCATLQYCPDPYIQRFVETPAHFSWKESYYRSTMSQSTQTNEFLSPEVFQHIWDFLEQPICSVQPIDLNFVDEPSEDGATNKIEISMDCIRMQD
- Theoretical MW (kDa):
- 36.63
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 8626
- GeneBank Accession#:
- BC039815
- Protein Accession#:
- AAH39815
- Gene Name:
- TP63
- Gene Alias:
- AIS,B(p51A),B(p51B),EEC3,KET,LMS,NBP,OFC8,RHS,SHFM4,TP53CP,TP53L,TP73L,p40,p51,p53CP,p63,p73H,p73L
- Gene Description:
- tumor protein p63
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq
- Other Designations:
- amplified in squamous cell carcinoma,chronic ulcerative stomatitis protein,keratinocyte transcription factor,transformation-related protein 63,tumor protein p53-competing protein,tumor protein p53-like,tumor protein p73-like
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Carcinoma, Transitional Cell
- Cleft Lip
- Cleft Palate
- Cognition Disorders
- Ectodermal Dysplasia
- Genetic Predisposition to Disease
- Lung Neoplasms
- Neoplasm Invasiveness
- Pulmonary Disease, Chronic Obstructive
- Syndrome
- Tobacco Use Disorder
- Urinary Bladder Neoplasms
- Werner syndrome